Epidemiological Approaches to Heart Disease: The Framingham Study

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The Framingham Heart Study

Previous reports indicate that cardiac output is increased early in the course of hypertension. The purpose of this study was to identify with echocardiography hemodynamic features in normotensive adults that predicted the development of hypertension. Framingham Heart Study subjects were eligible for this investigation if they were normotensive at the baseline examination (systolic blood pressu...

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The Framingham Heart Study

Background Sinking prebeta lipoprotein is a putative marker for elevated levels of lipoprotein (a). Although prospective data suggest that increased plasma lipoprotein (a) is an independent risk factor for coronary heart disease in men, no prospective studies are available in women. Methods and Results From 1968 through 1975, sinking prebeta lipoprotein was determined by paper electrophoresis i...

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Epidemiological Background and Design: the Framingham Study

The Framingham Heart Study is widely acknowledged as a premier longitudinal study. Several historical reviews of its background and design already exist (Dawber, 1980; Dawber, Kannel and Lyell, 1963; Dawber, Meadors and Moore, 1951; Dawber and Moore, 1952; Dawber, Moore and Mann, 1957; Feinlieb, 1983; Gordon and Kannel, 1968a; Gordon and Kannel, 1972 and Higgins, 1984). These were often written...

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Insulin resistance and the relationship of a dyslipidemia to coronary heart disease: the Framingham Heart Study.

OBJECTIVE The goal of this study was to examine the effect of insulin resistance (IR) in subjects without diabetes on the relationship of a dyslipidemia with high triglycerides and low high-density lipoprotein cholesterol (HDL-C) to the development of coronary heart disease (CHD). METHODS AND RESULTS Lower and higher fasting plasma HDL-C and triglyceride concentrations (defined at the study p...

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Incidence of Hypertension The Framingham Heart Study

Background Left ventricular hypertrophy is often found very early in the course of hypertension. It is not known whether increased left ventricular mass contributes to the pathogenesis of hypertension. The purpose of this study was to examine the impact of left ventricular mass and other echocardiographically assessed cardiac structural features on the incidence of hypertension. Methods and Res...

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ژورنال

عنوان ژورنال: American Journal of Public Health and the Nations Health

سال: 1951

ISSN: 0002-9572

DOI: 10.2105/ajph.41.3.279